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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AURKC
All Species:
35.15
Human Site:
Y122
Identified Species:
59.49
UniProt:
Q9UQB9
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQB9
NP_001015878.1
309
35591
Y122
R
V
Y
L
I
L
E
Y
A
P
R
G
E
L
Y
Chimpanzee
Pan troglodytes
XP_001142357
309
35587
Y122
R
V
Y
L
I
L
E
Y
A
P
R
G
E
L
Y
Rhesus Macaque
Macaca mulatta
XP_001098364
471
52859
F284
R
V
Y
L
I
L
E
F
A
P
R
G
E
L
Y
Dog
Lupus familis
XP_849906
346
39574
Y156
R
I
Y
L
I
L
E
Y
A
P
R
G
E
L
Y
Cat
Felis silvestris
Mouse
Mus musculus
O88445
282
32888
R107
E
L
Y
K
E
L
Q
R
H
Q
K
L
D
Q
Q
Rat
Rattus norvegicus
O55099
343
39216
Y159
R
I
Y
L
I
L
E
Y
A
P
R
G
E
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521399
303
34973
Y111
R
V
Y
L
I
L
E
Y
A
P
R
G
E
V
Y
Chicken
Gallus gallus
XP_425725
409
46456
Y226
R
V
Y
L
I
L
E
Y
A
P
R
G
E
V
F
Frog
Xenopus laevis
Q6GPL3
368
41997
F179
R
I
Y
L
M
L
E
F
A
P
R
G
E
L
Y
Zebra Danio
Brachydanio rerio
Q6NW76
320
36928
Y132
R
V
F
L
I
L
E
Y
A
P
R
G
E
M
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKN7
329
38282
I132
R
I
Y
L
A
L
E
I
A
S
E
G
E
L
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01427
305
34731
Y109
K
I
Y
L
V
L
E
Y
A
P
G
G
E
M
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q683C9
282
32738
E107
V
R
G
E
L
Y
K
E
L
Q
K
C
K
Y
F
Baker's Yeast
Sacchar. cerevisiae
P38991
367
42927
Y183
R
V
Y
L
L
M
E
Y
L
V
N
G
E
M
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
63.4
70.5
N.A.
72.4
67.3
N.A.
64.7
52.3
58.1
65.3
N.A.
43.1
N.A.
54.6
N.A.
Protein Similarity:
100
100
64.7
78.9
N.A.
82.5
79.3
N.A.
78.3
62.3
71.1
78.7
N.A.
62.6
N.A.
68.9
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
13.3
93.3
N.A.
93.3
86.6
80
86.6
N.A.
60
N.A.
66.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
40
100
N.A.
100
100
100
100
N.A.
73.3
N.A.
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.3
38.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.8
55.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
79
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
8
0
0
8
8
0
86
8
0
0
8
0
86
0
0
% E
% Phe:
0
0
8
0
0
0
0
15
0
0
0
0
0
0
22
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
8
86
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
36
0
0
58
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
8
0
0
8
0
0
0
15
0
8
0
0
% K
% Leu:
0
8
0
86
15
86
0
0
15
0
0
8
0
50
0
% L
% Met:
0
0
0
0
8
8
0
0
0
0
0
0
0
22
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
72
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
15
0
0
0
8
8
% Q
% Arg:
79
8
0
0
0
0
0
8
0
0
65
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
50
0
0
8
0
0
0
0
8
0
0
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
86
0
0
8
0
65
0
0
0
0
0
8
72
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _